CURRENT RESEARCH: Low vitamin D may be related to antibody levels and disease activity in children with lupus

11 Nov

New research published in Clinical Rheumatology found that children with systemic lupus erythematosus who have low vitamin D levels have increased disease activity and antibody levels.

Researchers out of Saudi Arabia recently recruited 28 children with lupus to study how vitamin D related to antibody levels and disease activity.

The researchers conducted an analysis of the baseline measurements. They found that vitamin D was inversely associated with disease activity and number of antibodies, meaning that higher vitamin D status was related to decreased disease activity and antibody count.

Vitamin D3 and calcium supplementation suggested a causal role for vitamin D in improving the health of lupus patients. After 3 months of supplementation, 17 patients had improved disease activity and antibody count.

“Disease activity of childhood lupus is probably linked with low serum vitamin D levels,” concluded the researchers.

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